It is not known whether the lung problems caused by amiodarone are due to direct damage by the drug to the lung’s tissues, to an immune reaction to the drug, or to some other mechanism. Amiodarone can cause numerous kinds of lung problems, but in most cases, the problem takes one of four forms. Amiodarone adsorbs to polyvinyl chloride tubing; however, current dosing recommendations appear to correct for this. Because of formation of precipitate, intravenous amiodarone should not be given concurrently with acetic acid, aminophylline, mezlocillin sodium, cefamandole nafate, cefazolin sodium, heparin sodium, sodium acetate, or quinidine gluconate. The mechanism of action of intravenous.